Written and illustrated by in the headline of the first compilation volume of the spin-off manga Tetsuji Kanie, Hataraku Saibou White ((White blood cells at work) was found to be the literary franchise of Hataraku Saibou ((Cells at work!) has more than five million copies in circulation. This count includes not only copies of the main series, but also of all derivative works.
On the other hand, Akane Shimizu published the original manga through the magazine Shonen Sirius monthly from the publisher Kodansha between January 2015 and January 2021. The publisher published the sixth and final compilation volume on February 9 in Japan, parallel to the first compilation volume of the spin-off manga Hataraku Saibou White.
The piece inspired a thirteen-episode anime adaptation produced by the studios. David production and published in July 2018. A second season with a director replacement was released in January 2021 and is confirmed with a total of eight episodes.
Synopsis of Hataraku Saibou
In the human body around 37.2 trillion cells are supplied with energy 24 hours a day, 365 days a year. The cheerful and somewhat airy Sekkekkyuu AE3803 (Erythrocyte AE3803) is ready to take on the important task of transporting oxygen. As usual, Hakkekkyuu U-1146 (Leukocyte U-1146) works hard to patrol and eliminate foreign bacteria that are trying to make the body their new hiding place. In other places, small tiles are lined up for a new construction project.
When dealing with injuries and allergies, loss of lungs, and battling similar cell types, the cells' daily life is always hectic as they work together to keep the body healthy.
Source: Official Twitter account
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